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KMID : 0043320080310101225
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Archives of Pharmacal Research
2008 Volume.31 No. 10 p.1225 ~ p.1229
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A New Stilbene Glucoside Gallate from the Roots of Polygonum multiflorum
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Ryu Shi-Yong
Kim Young-Kyoon
Lee Kang-Ro
Choi Yeon-Hee
Kim Ki-Hyun
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Abstract
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A new stilbenoid (1) was isolated from the root extract of Polygonum multiflorum together with eight known constituents (2~9). The chemical structure of 1 was established as the 6’’-O-monogalloyl ester of (E)-2,3,4’,5-β-tetrahydroxystilbene-2-β-D-glucopyranoside based on physicochemical and spectroscopic analyses, particularly by NMR spectroscopic data, i.e., COSY, HMQC and HMBC. Compound 1 weakly inhibited acetylcholinesterase in vitro.
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KEYWORD
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Polygonum multiflorum, Polygonaceae, (E)-2, 3, 4’, 5-tetrahydroxystilbene-2-β-D-glucoside, Stilbene glucoside gallate
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